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Starpharma Receives USD $5.5 Million Upfront Payment from Genentech

Oct 22, 2025

Starpharma Holdings Limited (ASX: SPL) has announced the receipt of an upfront payment of USD $5.5 million (AUD $8.5 million) from Genentech, a member of the Roche Group, following the recently established license agreement between the two companies. This collaboration marks the commencement of a development program using Starpharma’s proprietary DEP® dendrimer platform to create dendrimer-drug conjugates incorporating Genentech’s oncology medicines.

The agreement also includes potential development, commercial, and sales milestone payments of up to USD $564 million (AUD $869 million), along with tiered royalties on global net sales. Starpharma’s DEP® technology offers key benefits such as enhanced solubility, improved efficacy, controlled pharmacokinetics, and reduced toxicity. Its broad applicability across small molecules, peptides, proteins, and advanced therapeutic classes provides opportunities for partners to enhance product performance, expand treatment indications, and strengthen their pharmaceutical pipelines.

 

 

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