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Neuren Pharmaceuticals Shares Drop as Rett Syndrome Drug Sales Fall Short of Expectations

Nov 06, 2025

Highlights:

  • Neuren Pharmaceuticals reports slower-than-expected revenue growth for Rett syndrome treatment
  • Investors react negatively despite overall quarterly sales increase
  • Shares fall nearly 9% at the time of writing

Shares of Neuren Pharmaceuticals Limited (ASX: NEU) declined sharply in today’s trading session, falling around 8.9% at the time of writing, after the biotechnology company reported third-quarter sales growth that did not meet market expectations. The company announced that sales of its Rett syndrome therapy increased by 11% during the quarter, which, although positive in absolute terms, was below the robust momentum investors had anticipated.

Market Reaction and Investor Sentiment

Neuren has been under keen market focus due to strong enthusiasm surrounding its treatment targeting Rett syndrome, a rare neurodevelopmental disorder that predominantly affects young girls. The therapy has been viewed as a key revenue driver and a significant milestone for the company in the global rare disease market.

However, analysts noted that the latest sales performance suggests a slower ramp-up phase than initially projected. As a result, trading sentiment turned bearish, with Neuren Pharmaceuticals Limited’s share price slipping to around $18.40, down by approximately 9.04% at the time of writing.

Growth Potential Remains, But Expectations Need Balancing

Despite the market’s reaction, some analysts argue that the long-term commercial opportunity remains intact. Rett syndrome treatments are part of a highly specialized medical niche, and uptake often evolves gradually due to diagnostic complexity and regulatory pathways across regions.

Neuren's management continues to emphasize global outreach efforts, partnerships with healthcare networks, and education initiatives to broaden accessibility and treatment awareness.

For now, investors appear to be recalibrating expectations — shifting from rapid revenue acceleration towards a steadier, more progressive commercialization outlook.

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