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AdAlta and AdCella Partner with SHcell to Globalise Breakthrough CAR-T Cancer Therapy.

AdAlta Limited (ASX: 1AD) and its cellular immunotherapy subsidiary, AdCella, have entered a strategic Development and Collaboration Agreement with Shanghai Cell Therapy Group to co-develop and commercialise BZDS1901 outside Greater China. The deal launches AdCella’s “East to West” strategy, combining Chinese innovation with Australia’s clinical and manufacturing expertise.

BZDS1901 is a first-in-class, PD1-armoured CAR-T therapy targeting mesothelin, a protein highly expressed in aggressive solid tumours such as mesothelioma. Early clinical data from China has demonstrated compelling response rates, including complete responses, alongside a faster and lower-cost manufacturing process compared with conventional CAR-T therapies.

Under the agreement, AdCella will fund and lead development outside China, establish Australian manufacturing, and conduct Phase 1 clinical trials, while SHcell continues development in China. The collaboration provides AdCella exposure to future commercialisation proceeds and positions AdAlta at the forefront of next-generation cellular immunotherapies addressing major unmet needs.

 

 

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