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Mesoblast Appoints New CFO to Strengthen Commercial Expansion

Nov 17, 2025

Mesoblast Limited (ASX: MSB) has named James M. O’Brien as its U.S.-based Chief Financial Officer, a move that underscores the company’s ongoing transition toward functioning as a fully integrated commercial enterprise. O’Brien brings extensive financial management experience across global life sciences and pharmaceutical companies, including senior roles at Actavis, Allergan, Nycomed, Cognition Therapeutics, and Faron Pharmaceuticals. His background spans corporate finance, forecasting, acquisitions, and operational oversight, with involvement in transactions exceeding AU$10 billion.

Mesoblast’s leadership highlighted that O’Brien’s expertise will support the commercialization of Ryoncil®, the first FDA-approved mesenchymal stromal cell therapy for pediatric SR-aGvHD, while strengthening governance and financial controls. The company continues advancing its allogeneic cell therapy pipeline targeting inflammatory conditions, heart failure, and chronic low back pain, supported by an extensive global patent portfolio and international commercial partnerships.

 

 

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