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Neuren Reports Strong Royalty Growth as DAYBUE Sales Hit US$101.1 Million in Q3 2025.

Nov 06, 2025

Neuren Pharmaceuticals Limited (ASX: NEU) recorded a strong third quarter in 2025, supported by impressive sales growth of DAYBUE (trofinetide). The product achieved net sales of US$101.1 million, an 11% increase compared to Q3 2024 and 5% higher than Q2 2025. During the quarter, more than 1,000 patients received shipments for the first time, with rising adoption from community-based physicians. Neuren’s royalty income reached AU$16.4 million, up 24% year-on-year, with projected full-year royalties expected between AU$63 million and A$66 million, based on Acadia’s revised sales guidance of US$385–400 million. 

International progress continues, with a Phase 3 trial underway in Japan and patient access programs established across Europe, Israel, the Middle East, and Latin America. A regulatory opinion from the EU’s CHMP is anticipated in early 2026, underscoring DAYBUE’s expanding global footprint and Neuren’s strengthening royalty outlook.

 

 

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